Sobel Jack D, Nyirjesy Paul, Kessary Hadar, Ferris Daron G
Department of Internal Medicine, Wayne State University, Detroit, Michigan, USA.
J Womens Health (Larchmt). 2009 Sep;18(9):1467-70. doi: 10.1089/jwh.2008.1305.
Although pH assessment of vaginal secretions is beneficial for diagnosing vaginitis, it is not commonly done. The purpose of this study was to determine the performance characteristics of the VS-Sense (pH test) swab (Common Sense, Ltd., Caesarea, Israel) in augmenting the diagnosis of vaginitis.
We prospectively studied 193 women with acute vulvovaginal symptoms and 74 asymptomatic controls at three medical centers. The VS-Sense swab was administered intravaginally, and results were interpreted by a nurse. These results were compared with final clinical and laboratory diagnoses.
In women with an elevated pH caused by bacterial vaginosis (BV), trichomonas, and other types of vaginitis, the VS-Sense test sensitivity and specificity were 82.3% (102 of 124) (95% CI 74.4%-88.5%) and 94.2% (129 of 137) (95% CI 88.8%-97.4%), respectively. There was an 86.2% (95% CI 81.3%-90.1%) overall agreement between pH paper and VS-Sense swab results.
The VS-Sense test offers an alternative approach to measuring vaginal pH with nitrazine paper. Use of this simple, more rapid test may facilitate the diagnosis of vulvovaginitis.
尽管评估阴道分泌物的pH值有助于诊断阴道炎，但这一操作并不常见。本研究的目的是确定VS-Sense（pH测试）拭子（常识有限公司，以色列凯撒利亚）在辅助诊断阴道炎方面的性能特征。
我们在三个医疗中心对193名有急性外阴阴道症状的女性和74名无症状对照者进行了前瞻性研究。将VS-Sense拭子插入阴道内，由一名护士解读结果。将这些结果与最终的临床和实验室诊断结果进行比较。
在因细菌性阴道病（BV）、滴虫及其他类型阴道炎导致pH值升高的女性中，VS-Sense测试的敏感性和特异性分别为82.3%（124例中的102例）（95%可信区间74.4%-88.5%）和94.2%（137例中的129例）（95%可信区间88.8%-97.4%）。pH试纸与VS-Sense拭子结果的总体一致性为86.2%（95%可信区间81.3%-90.1%）。
VS-Sense测试为使用硝嗪纸测量阴道pH值提供了另一种方法。使用这种简单、更快速的测试可能有助于外阴炎和阴道炎的诊断。
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