[The OTT-MAL fusion oncogene: another Notch in megakaryoblastic leukemia].

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作者信息

Bernard Olivier A, Gilliland D Gary, Mercher Thomas

出版信息

Med Sci (Paris). 2009 Aug-Sep;25(8-9):676-8. doi: 10.1051/medsci/2009258-9676.

DOI:10.1051/medsci/2009258-9676

PMID:19765378

Abstract

摘要

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[The OTT-MAL fusion oncogene: another Notch in megakaryoblastic leukemia].

Med Sci (Paris). 2009 Aug-Sep;25(8-9):676-8. doi: 10.1051/medsci/2009258-9676.

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.

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High incidence of CALM-AF10 fusion and the identification of a novel fusion transcript in acute megakaryoblastic leukemia in children without Down's syndrome.

Leukemia. 2007 Feb;21(2):352-3. doi: 10.1038/sj.leu.2404503. Epub 2006 Dec 14.

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