Department of Radiology, Faculty of Medicine, Baskent University, Dadaloglu Mahallesi, Adana, Turkey.
Cardiovasc Intervent Radiol. 2010 Feb;33(1):18-24. doi: 10.1007/s00270-009-9691-7. Epub 2009 Sep 19.
The aim of this study was to report technical details, procedure-related complications, and results of endovascular treatment in chronic iliac artery occlusion. Between 2001 and 2008, endovascular treatments of 127 chronic iliac artery occlusions in 118 patients (8 women and 110 men; mean age, 59 years) were retrospectively reviewed. The study was based on Ad Hoc Committee on Reporting Standards (Society for Vascular Surgery/International Society for Cardiovascular Surgery Standards). All occlusions were treated with stent placement with or without preliminary balloon angioplasty. Kaplan-Meier estimators were used to determine patency rates. Univariate and multivariate analyses were performed to determine variables affecting successful recanalization, major complications, early stent thrombosis (<or=30 days), and primary and secondary patency rates. Initial technical success was achieved in 117 (92%) procedures. Successful recanalization was obtained by antegrade approach in 69 of 77 (90%) procedures and by retrograde approach in 52 of 105 (50%) procedures (p < 0.001). Complications were encountered in 28 (24%) patients [minor in 7 patients (6%) and major in 22 patients (19%)]. One death occurred in the operative period secondary to iliac artery rupture. Early stent thrombosis was seen in eight (7%) patients. Presence of critical limb ischemia (p = 0.03), subintimal recanalization (p = 0.03), and major complication (p = 0.02) were the independent predictors of early stent thrombosis on multivariate analysis. Primary and secondary patency rates at 5 years were 63 and 93%, respectively. Presence of critical limb ischemia, TASC type C iliac lesions, combined occlusions of both common and external iliac arteries, and major complications were associated with decreased patency rates on univariate analysis, whereas these factors were not independent predictors of stent patency on multivariate analysis. In conclusion, endovascular treatment of iliac artery occlusion has a high technical success rate with favorable long-term patency rate. Success of recanalization increases with use of the antegrade approach and with the presence of a stump of artery before the occlusion.
本研究旨在报告慢性髂动脉闭塞的血管内治疗的技术细节、与操作相关的并发症和结果。2001 年至 2008 年,回顾性分析了 118 例患者(8 名女性,110 名男性;平均年龄 59 岁)的 127 例慢性髂动脉闭塞的血管内治疗。该研究基于报告标准的特设委员会(血管外科学会/心血管外科学会国际标准)。所有闭塞均采用支架置入术治疗,其中包括或不包括初步球囊血管成形术。Kaplan-Meier 估计器用于确定通畅率。进行单变量和多变量分析以确定影响成功再通、主要并发症、早期支架内血栓形成(≤30 天)以及原发性和继发性通畅率的变量。117 例(92%)操作初始技术成功。69 例(90%)通过顺行途径成功再通,105 例(50%)通过逆行途径成功再通(p<0.001)。28 例(24%)患者出现并发症[7 例(6%)为轻微并发症,22 例(19%)为严重并发症]。1 例患者死于术中髂动脉破裂。8 例(7%)患者出现早期支架内血栓形成。多变量分析显示,存在严重肢体缺血(p=0.03)、内膜下再通(p=0.03)和主要并发症(p=0.02)是早期支架内血栓形成的独立预测因素。5 年时的原发性和继发性通畅率分别为 63%和 93%。单变量分析显示,存在严重肢体缺血、TASC C 型髂动脉病变、股总动脉和股外动脉同时闭塞以及主要并发症与较低的通畅率相关,而多变量分析显示这些因素不是支架通畅的独立预测因素。总之,髂动脉闭塞的血管内治疗具有较高的技术成功率和良好的长期通畅率。再通成功率随着顺行途径的使用以及闭塞前动脉残端的存在而增加。