老年患者中肾细胞癌合并IgA肾病
Renal cell carcinoma in association with IgA nephropathy in the elderly.
作者信息
Mimura Imari, Tojo Akihiro, Kinugasa Satoshi, Uozaki Hiroshi, Fujita Toshiro
机构信息
Division of Nephrology and Endocrinology, Department of Internal Medicine, University of Tokyo, Tokyo, Japan.
出版信息
Am J Med Sci. 2009 Nov;338(5):431-2. doi: 10.1097/MAJ.0b013e3181ae1b12.
PMID:19773639
Abstract
IgA nephropathy can occur as a paraneoplastic syndrome of renal cell carcinoma. We report 3 cases of IgA nephropathy associated with renal cell carcinoma in the elderly patients and demonstrate that infiltrating lymphocytes and plasma cells around renal cell carcinoma produce IgA that likely contributed to mesangial IgA deposition.
摘要
IgA肾病可作为肾细胞癌的副肿瘤综合征出现。我们报告了3例老年患者中与肾细胞癌相关的IgA肾病病例，并证明肾细胞癌周围浸润的淋巴细胞和浆细胞产生IgA，这可能促成了系膜IgA沉积。
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