Jonasson Grethe, Alstad Torgny, Vahedi Flor, Bosaeus Ingvar, Lissner Lauren, Hakeberg Magnus
Research and Development Center in Southern Alvsborg County, Borås, Sweden.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Oct;108(4):e42-51. doi: 10.1016/j.tripleo.2009.05.018.
This investigation analyzed the use of mandibular sparse trabeculation as a fracture risk indicator.
Trabeculation was classified as sparse, alternating dense and sparse, or dense using intraoral radiographs from 274 men and women (50-87 years old) including 56 with previous reported fractures. Mandibular bone texture was assessed on digitized radiographs.
Forty-eight percent of subjects with sparse trabeculation reported fractures, compared with 19% with alternating sparse and dense trabeculation and 2% with dense trabeculation (Kruskal-Wallis test: P < .00001). Logistic regression analysis showed that sparse trabeculation (odds ratio [OR] = 5.9; 95% CI 3.0-11.1; P < .0001) and lowest bone texture classes (OR = 2.2; 95% CI 1.0-4.5; P = .04) were associated with an increased fracture risk, especially for subjects > or =75 years (OR = 7.1; 95% CI 2.5-20.0; P = .0002).
Fracture risk was increased in subjects with sparse alveolar trabecular pattern. Dentists may be able to identify high-risk subjects before fracture.
本研究分析下颌骨小梁稀疏作为骨折风险指标的应用情况。
利用274名年龄在50至87岁之间的男性和女性(其中56人曾有骨折报告)的口腔内X光片,将小梁情况分为稀疏、疏密交替或致密。在数字化X光片上评估下颌骨纹理。
小梁稀疏的受试者中有48%曾发生骨折,相比之下,小梁疏密交替的受试者中这一比例为19%,小梁致密的受试者中为2%(Kruskal-Wallis检验:P <.00001)。逻辑回归分析显示,小梁稀疏(比值比[OR]=5.9;95%置信区间3.0 - 11.1;P <.0001)和最低骨纹理等级(OR = 2.2;95%置信区间1.0 - 4.5;P =.04)与骨折风险增加相关,尤其是对于年龄≥75岁的受试者(OR = 7.1;95%置信区间2.5 - 20.0;P =.0002)。
牙槽骨小梁模式稀疏的受试者骨折风险增加。牙医或许能够在骨折前识别出高危受试者。