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胃肠道对心脏电生理学的影响:肠道内肌电解偶联诱发心律失常发作。

Gastrointestinal influence on the electrophysiology of the heart: induction of cardiac arrhythmic episodes by myoelectrical uncoupling within the gut.

作者信息

Powers Dale

出版信息

J Smooth Muscle Res. 2009 Aug;45(4):139-48. doi: 10.1540/jsmr.45.139.

Abstract

It is theorized that the triggering of some arrhythmic episodes in cardiac-sensitive subjects might be directly linked to the functional uncoupling of gastro myoelectrical activity following the consumption of particular foods or by other influences on the gut. The intent of this research is to reveal the likely adverse mechanism involved through investigative analytical review. The resulting evidence shows there exists a triggering source within the visceral smooth muscle system of the gut and a mode of transmission incorporated in the autonomic nervous system mediated by the central autonomic network that could significantly affect the electrophysiology of the heart. A formal clinical study is indicated to determine the specific types of troublesome foods and other factors associated to better understand the overall process.

摘要

理论认为,心脏敏感人群中某些心律失常发作的触发可能与食用特定食物后胃肠电活动的功能性解偶联或肠道受到的其他影响直接相关。本研究的目的是通过调查性分析综述揭示其中可能涉及的不良机制。研究结果表明,肠道内脏平滑肌系统中存在一个触发源,以及由中枢自主神经网络介导的自主神经系统中的一种传播模式,这可能会显著影响心脏的电生理。需要进行一项正式的临床研究,以确定引发问题的具体食物类型和其他相关因素,从而更好地了解整个过程。

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