Thatipelli Mallik, Misra Sanjay
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Abdom Imaging. 2010 Oct;35(5):612-21. doi: 10.1007/s00261-009-9572-1.
Renovascular diseases are common conditions with important implications on cardiovascular morbidity and mortality. Renal artery stenosis (RAS) is present in 1-5% of patients with hypertension (HTN) in the US with the vast majority of caused by atherosclerosis. Atherosclerotic RAS is related not only to uncontrolled HTN, but also to renal dysfunction. Atherosclerotic RAS in the USA has been reported to account for approximately 14-16% of new patients requiring dialysis each year. Hence a concerted effort was made in the last decade to treat renovascular stenosis using newly developed endovascular therapies to improve cardiovascular morbidity and renal function. A review on new advances in the endovascular management of renal artery stenosis with low profile stents, embolic protection devices, and drug eluting stents is presented.
肾血管疾病是常见病症,对心血管发病率和死亡率有重要影响。在美国,1%-5%的高血压(HTN)患者存在肾动脉狭窄(RAS),其中绝大多数由动脉粥样硬化引起。动脉粥样硬化性RAS不仅与未控制的高血压有关,还与肾功能不全有关。据报道,在美国,动脉粥样硬化性RAS约占每年需要透析的新患者的14%-16%。因此,在过去十年中,人们齐心协力使用新开发的血管内治疗方法来治疗肾血管狭窄,以改善心血管发病率和肾功能。本文综述了使用低轮廓支架、栓塞保护装置和药物洗脱支架进行肾动脉狭窄血管内治疗的新进展。