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老年人高血压:治疗可能使老年人受益的新证据与旧证据。

Hypertension in the elderly: new and old evidence that treatment may benefit the old.

作者信息

Fagard Robert H

机构信息

Hypertension and Cardiovascular Rehabilitation Unit, Faculty of Medicine, University of Leuven, Leuven, Belgium.

出版信息

J Nephrol. 2009 Sep-Oct;22(5):580-6.

Abstract

Hypertension is prevalent and remains an important risk factor in elderly and very elderly. Randomized controlled outcome trials have shown benefit of antihypertensive treatment in patients with systolic diastolic hypertension and in patients with isolated systolic hypertension, aged 60 years and over. More recently benefit has also been shown in octogenerians with hypertension. Overall there is no strong evidence that protection against major cardiovascular events afforded by different drug classes varies substantially with age. Finally, blood pressure lowering therapy also improves prognosis in hypertensive patients with type 2 diabetes.

摘要

高血压很常见,并且仍然是老年人和高龄老人的一个重要危险因素。随机对照结局试验表明,降压治疗对60岁及以上的收缩期舒张期高血压患者和单纯收缩期高血压患者有益。最近,也已证明降压治疗对八旬高血压患者有益。总体而言,没有强有力的证据表明不同药物类别对主要心血管事件的预防作用会随年龄有很大差异。最后,降压治疗也可改善2型糖尿病高血压患者的预后。

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