De Silva Mary, Maclachlan Malcolm, Devane Declan, Desmond Deirdre, Gallagher Pamela, Schnyder Ulrich, Brennan Muireann, Patel Vikram
Nutrition & Public Health Intervention Research Unit, London School of Hygiene & Tropical Medicine, Keppel Street, London, UK, WC1E 7HT.
Cochrane Database Syst Rev. 2009 Oct 7;2009(4):CD006422. doi: 10.1002/14651858.CD006422.pub3.
Traumatic physical injury can result in many disabling sequelae including physical and mental health problems and impaired social functioning.
To assess the effectiveness of psychosocial interventions in the prevention of physical, mental and social disability following traumatic physical injury.
The search was not restricted by date, language or publication status. We searched the following electronic databases; Cochrane Injuries Group Specialised Register, CENTRAL (The Cochrane Library 2009, Issue 1), MEDLINE (Ovid SP), EMBASE (Ovid SP), PsycINFO (Ovid SP), Controlled Trials metaRegister (www.controlled-trials.com), AMED (Allied & Complementary Medicine), ISI Web of Science: Social Sciences Citation Index (SSCI), PubMed. We also screened the reference lists of all selected papers and contacted authors of relevant studies. The latest search for trials was in February 2008.
Randomised controlled trials that consider one or more defined psychosocial interventions for the prevention of physical disability, mental health problems or reduced social functioning as a result of traumatic physical injury. We excluded studies that included patients with traumatic brain injury (TBI).
Two authors independently screened the titles and abstracts of search results, reviewed the full text of potentially relevant studies, independently assessed the risk of bias and extracted data.
We included five studies, involving 756 participants. Three studies assessed the effect of brief psychological therapies, one assessed the impact of a self-help booklet, and one the effect of collaborative care. The disparate nature of the trials covering different patient populations, interventions and outcomes meant that it was not possible to pool data meaningfully across studies. There was no evidence of a protective effect of brief psychological therapy or educational booklets on preventing disability. There was evidence from one trial of a reduction in both post-traumatic stress disorder (PTSD) and depressive symptoms one month after injury in those who received a collaborative care intervention combined with a brief psycho-educational intervention, however this was not retained at follow up. Overall mental health status was the only disability outcome affected by any intervention. In three trials the psychosocial intervention had a detrimental effect on the mental health status of patients.
AUTHORS' CONCLUSIONS: This review provides no convincing evidence of the effectiveness of psychosocial interventions for the prevention of disability following traumatic physical injury. Taken together, our findings cannot be considered as supporting the provision of psychosocial interventions to prevent aspects of disability arising from physical injury. However, these conclusions are based on a small number of disparate trials with small to moderate sample sizes and are therefore necessarily cautious. More research, using larger sample sizes, and similar interventions and patient populations to enable pooling of results, is needed before these findings can be confirmed.
创伤性身体损伤可导致许多致残后遗症,包括身心健康问题及社会功能受损。
评估心理社会干预措施在预防创伤性身体损伤后出现身体、心理和社会残疾方面的有效性。
检索不受日期、语言或出版状态限制。我们检索了以下电子数据库:Cochrane损伤组专业注册库、CENTRAL(Cochrane图书馆2009年第1期)、MEDLINE(Ovid SP)、EMBASE(Ovid SP)、PsycINFO(Ovid SP)、对照试验元注册库(www.controlled-trials.com)、AMED(联合与补充医学)、ISI科学网:社会科学引文索引(SSCI)、PubMed。我们还筛选了所有入选论文的参考文献列表,并联系了相关研究的作者。最近一次试验检索时间为2008年2月。
随机对照试验,这些试验考虑了一种或多种明确的心理社会干预措施,用于预防创伤性身体损伤导致的身体残疾、心理健康问题或社会功能减退。我们排除了纳入创伤性脑损伤(TBI)患者的研究。
两位作者独立筛选检索结果的标题和摘要,审查潜在相关研究的全文,独立评估偏倚风险并提取数据。
我们纳入了五项研究,涉及756名参与者。三项研究评估了简短心理治疗的效果,一项评估了自助手册的影响,一项评估了协作护理的效果。涵盖不同患者群体、干预措施和结局的试验性质各异,这意味着无法在各项研究之间进行有意义的数据合并。没有证据表明简短心理治疗或教育手册对预防残疾有保护作用。有一项试验的证据表明,接受协作护理干预并结合简短心理教育干预的患者在受伤后一个月创伤后应激障碍(PTSD)和抑郁症状均有所减轻,但随访时未保持这一效果。总体心理健康状况是唯一受任何干预措施影响的残疾结局。在三项试验中,心理社会干预对患者的心理健康状况有不利影响。
本综述没有提供令人信服的证据表明心理社会干预措施对预防创伤性身体损伤后的残疾有效。综上所述,我们的研究结果不能被视为支持提供心理社会干预措施来预防身体损伤引起的残疾。然而,这些结论基于少数样本量小至中等的不同试验,因此必然较为谨慎。在这些发现得到证实之前,需要进行更多研究,采用更大样本量以及相似的干预措施和患者群体以便合并结果。