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A new way to classify genetic skin disease.

作者信息

Moss Celia

机构信息

Department of Dermatology, Birmingham Children's Hospital, Birmingham, UK.

出版信息

J Invest Dermatol. 2009 Nov;129(11):2543-5. doi: 10.1038/jid.2009.292.

Abstract

Genetic disorders with skin manifestations often affect other organs as well, and diseases with a similar array of features might be linked pathogenetically. Classifying disorders by individual phenotypic components may reveal clusters with a common genetic cause and elucidate pathogenic links. If components are categorized inadequately, however, the method will simply confirm what is known, obscure true links, and suggest false ones.

摘要

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