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[十二指肠消化性溃疡、迷走神经切断术后溃疡复发及佐林格-埃利森综合征时胃黏膜形态学改变的特征]

[The characteristics of the morphological changes in the gastric mucosa in duodenal peptic ulcer, ulcer recurrence after vagotomy and in the Zollinger-Ellison syndrome].

作者信息

Trofimov V M, Nechaĭ A I, Kalashnikov S A, Zuev V K, Movchan K N, Arkhipov V F, Ivanov G N

出版信息

Vestn Khir Im I I Grek. 1990 Nov;145(11):28-33.

PMID:1983173
Abstract

Results of morphometry and count of certain kinds of endocrinocytes of gastric mucosa are analyzed. Pronounced proliferative alterations of the gastric mucosa were found with clear signs of the increased function of the structures responsible for acid gastric secretion. In part of the patients with ulcer disease of the duodenum there are considerable changes in the amount of certain kinds of endocrinocytes of the antral portion of the stomach, which form accumulations in the form of different fields and even focal zones. Such alterations in the gastric mucosa have correlative relationships with the level of acid gastric secretion.

摘要

对胃黏膜某些类型内分泌细胞的形态计量学和计数结果进行了分析。发现胃黏膜有明显的增殖性改变,负责胃酸分泌的结构功能增强的迹象明显。在部分十二指肠溃疡病患者中,胃窦部某些类型内分泌细胞的数量有相当大的变化,这些细胞形成不同区域甚至局灶性区域形式的聚集。胃黏膜的这种改变与胃酸分泌水平存在相关关系。

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