Escudero D, Matesanz R, Soratti C A, Flores José Ignacio
Servicio de Medicina Intensiva y Coordinación de Trasplantes, Hospital Universitario Central de Asturias, Oviedo, España.
Med Intensiva. 2009 Dec;33(9):415-23. doi: 10.1016/j.medin.2009.07.011.
To examine the diagnosis of brain death (BD) in Latin America.
The term BD has long been used to define the death of an individual despite legal differences and variations in the diagnostic criteria applied in each country.
A survey was conducted to gain information on the medical and legal diagnosis of BD in the 21 countries that make up the Latin American Network/Council of Donation and Transplant.
All the Latin American countries except for Nicaragua legally recognize BD as the death of the person. To declare a person dead, 2 or 3 doctors are required in most countries. In all the countries, the requirements that must be fulfilled are unresponsive coma, lack of brainstem reflexes and of spontaneous breathing. Partial pressure of arterial carbon dioxide levels required in the apnea test vary from 50-60mm Hg. The minimum temperature required for a neurological examination ranges from 32 degrees -35 degrees C. The atropine test is mandatory in 7 (35%) countries. The most recommended observation period is 6h, but there is great variation and can be up to 24h. In 8 countries (40%), an instrumental test is obligatory, while in the remaining countries this is only undertaken under special circumstances. In some countries, when organs are not donated for transplant, support measures are not withdrawn, this being more frequent in children.
There seems to be some uniformity in the main diagnostic criteria applied, with differences observed in clinical prerequisites, neurological exams, observation time, instrumental tests and the clinical decisions made following a declaration of BD. It is recommended that diagnostic criteria be standardized.
探讨拉丁美洲脑死亡(BD)的诊断情况。
尽管各国在法律以及所应用的诊断标准上存在差异,但长期以来一直使用脑死亡这一术语来定义个体的死亡。
对组成拉丁美洲捐赠与移植网络/理事会的21个国家进行了一项调查,以获取有关脑死亡医学和法律诊断的信息。
除尼加拉瓜外,所有拉丁美洲国家均在法律上承认脑死亡为人的死亡。在大多数国家,宣布一个人死亡需要2名或3名医生。在所有国家,必须满足的条件是无反应性昏迷、缺乏脑干反射和自主呼吸。呼吸暂停试验所需的动脉二氧化碳分压水平在50 - 60毫米汞柱之间。神经学检查所需的最低体温范围为32摄氏度至35摄氏度。7个(35%)国家强制进行阿托品试验。最推荐的观察期为6小时,但差异很大,可达24小时。在8个国家(40%),仪器检查是强制性的,而在其余国家,仅在特殊情况下进行。在一些国家,当器官不用于移植捐赠时,不撤销支持措施,这种情况在儿童中更为常见。
在所应用的主要诊断标准方面似乎存在一些一致性,但在临床前提条件、神经学检查、观察时间、仪器检查以及脑死亡宣布后的临床决策方面存在差异。建议对诊断标准进行标准化。