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血液透析患者颅内动脉钙化。

Intracranial artery calcification in hemodialysis patients.

出版信息

Int Urol Nephrol. 2011 Jun;43(2):585-8. doi: 10.1007/s11255-009-9664-4. Epub 2009 Oct 23.

Abstract

Intracranial artery calcification is an independent risk factor for ischemic stroke, and while it is frequently observed on computed tomographic images of the brain in hemodialysis patients, its distribution has not been well studied. Fifty patients on maintenance hemodialysis were enrolled in this study. We divided the patients with intracranial artery calcification into two groups according to the duration of maintenance hemodialysis and compared the frequency of intracranial calcification of each of the intracranial arteries between the two groups. Intracranial artery calcification was found in 36 of the 50 hemodialysis patients. Among the 36 patients with intracranial artery calcification, the prevalence of calcification of each of the arteries was as follows: vertebral artery, 58.3%; internal carotid artery, 61.1%; basilar artery, 41.7%; anterior cerebral artery, 16.7%; middle cerebral artery, 30.6%; posterior cerebral artery, 8.3%. The prevalence of calcification of each of the intracranial arteries did not differ significantly between the patients with a hemodialysis duration of more than 20 years and those less than 20 years. The most frequently involved site of calcification was the internal carotid artery. The prevalence of calcification of the other intracranial arteries, particularly of the basilar artery, were relatively high. The prevalence of calcification of each of the intracranial arteries did not differ significantly between the patients with a hemodialysis duration of more than 20 years and less than 20 years.

摘要

颅内动脉钙化是缺血性卒中的独立危险因素,虽然在血液透析患者的脑部计算机断层扫描图像中经常观察到,但对其分布情况的研究还不够充分。本研究纳入了 50 名维持性血液透析患者。我们根据维持性血液透析的时间将颅内动脉钙化患者分为两组,并比较了两组患者颅内各动脉钙化的频率。在 50 名血液透析患者中,有 36 名患者存在颅内动脉钙化。在 36 名存在颅内动脉钙化的患者中,各动脉钙化的患病率如下:椎动脉 58.3%;颈内动脉 61.1%;基底动脉 41.7%;大脑前动脉 16.7%;大脑中动脉 30.6%;大脑后动脉 8.3%。透析时间超过 20 年和不足 20 年的患者,颅内各动脉钙化的患病率无显著差异。钙化最常累及的部位是颈内动脉。其他颅内动脉,特别是基底动脉的钙化患病率相对较高。透析时间超过 20 年和不足 20 年的患者,颅内各动脉钙化的患病率无显著差异。

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