使用生物胶成功实现手术性支气管胸膜瘘的支气管内封堵。

Successful endobronchial seal of surgical bronchopleural fistulas using BioGlue.

作者信息

Ranu Harpreet, Gatheral Timothy, Sheth Abhijat, Smith Edward E J, Madden Brendan P

机构信息

Department of Cardiothoracic Surgery, St. George's Hospital, London, United Kingdom.

出版信息

Ann Thorac Surg. 2009 Nov;88(5):1691-2. doi: 10.1016/j.athoracsur.2009.03.012.

DOI:10.1016/j.athoracsur.2009.03.012

PMID:19853144

Abstract

Postoperative bronchopleural fistula is uncommon, but it is associated with a high mortality and morbidity, and a prolonged hospital stay. Surgical treatment is gold standard, but it can prove challenging especially in the presence of infection. We describe three cases of bronchopleural fistula that developed after surgery for lung cancer in 1 patient and for bronchiectasis in 2 patients. All were successfully treated endoscopically by direct application of albumin-glutaraldehyde tissue adhesive (BioGlue; Cryolife Inc, Kennesaw, GA) through a rigid bronchoscope. Complete resolution was obtained in each patient within 24 hours.

摘要

术后支气管胸膜瘘并不常见，但它与高死亡率、高发病率以及延长的住院时间相关。手术治疗是金标准，但尤其在存在感染的情况下可能具有挑战性。我们描述了1例肺癌手术后及2例支气管扩张症手术后发生支气管胸膜瘘的病例。所有病例均通过硬支气管镜直接应用白蛋白 - 戊二醛组织粘合剂（BioGlue；Cryolife公司，美国佐治亚州肯尼索）成功进行了内镜治疗。每位患者在24小时内均实现了完全愈合。