Institute of Pathology, Western Reserve University and the University Hospitals, Cleveland.
J Exp Med. 1940 Apr 30;71(5):585-90. doi: 10.1084/jem.71.5.585.
Oxidized and reduced proteins were prepared from the ocular lenses of sheep, swine, chicken and fish (pike). The proteins were prepared under conditions designed to avoid denaturation and to produce relatively pure compounds. Serologic studies revealed that species specificity is demonstrable in the proteins from chicken and fish lenses, but in the more closely related species (swine and sheep) this characteristic is not so evident. Serologic differences may be detected in the lens preparations from a single species, depending on the redox state of the protein.
从绵羊、猪、鸡和鱼(梭子鱼)的眼睛晶状体中制备了氧化和还原蛋白。这些蛋白质是在避免变性和产生相对纯净化合物的条件下制备的。血清学研究表明,鸡和鱼晶状体中的蛋白质具有明显的种属特异性,但在亲缘关系较近的物种(猪和羊)中,这种特性并不明显。根据蛋白质的氧化还原状态,在同一物种的晶状体制剂中可能会检测到血清学差异。