HIV感染的实验室诊断

Laboratory diagnosis of HIV infection.

作者信息

Krasinski K, Borkowsky W

机构信息

Department of Pediatrics, New York University Medical Center, New York.

出版信息

Pediatr Clin North Am. 1991 Feb;38(1):17-35. doi: 10.1016/s0031-3955(16)38040-3.

DOI:10.1016/s0031-3955(16)38040-3

PMID:1987516

Abstract

Laboratory diagnosis of human immunodeficiency virus (HIV) infection is complicated by absence of data on sensitivity, specificity and predictive value of the various tests as they apply to children. The presence of maternal anti-HIV passively transmitted across the placenta also confounds diagnosis. The authors review currently available data on the detection of HIV, HIV genome, and HIV gene products, as well as the diagnostic value of detecting serologic and cellular responses to HIV in infants and children.

摘要

人类免疫缺陷病毒（HIV）感染的实验室诊断因缺乏各种检测方法应用于儿童时的敏感性、特异性和预测价值的数据而变得复杂。母体抗HIV通过胎盘被动传播的情况也会干扰诊断。作者回顾了目前关于检测HIV、HIV基因组和HIV基因产物的可用数据，以及检测婴儿和儿童对HIV的血清学和细胞反应的诊断价值。