Bibikov N G, Nizamov S V
Biofizika. 2009 Sep-Oct;54(5):921-34.
A method for the construction of shuffled autocorrelation functions was used to characterize single units located in the cochlear nucleus of grassy frog (Rana temporaria). A continuous characteristic frequency tone modulated by repeating pieces of low-frequency noises was used as a stimulus. This function was calculated as the correlation between the firing discharges evoked by different repeating pieces of the low-frequency noise. This approach allows one to exclude the influence of refractoriness and also considerably increases the repres. A comparison of the shiffled autocorrelation function with the conventional autocorrelation function allows one to estimate the temporal dynamics of changes in the postspike excitability of the neuron. An analysis of several examples demonstrates the possibility of facilitation just after the period of absolute refractoriness in some tonic units. Neurons demonstrating only a phasic response to the onset of unmodulated voice-frequency pieces were capable to selectively respond to special moments of noise amplitude modulation. These cells demonstrate an extremely high synchronism of reaction. In the cochlear nucleus of the frog, we described a neuron characterized by the internal periodicity of firing, which is not connected with the dynamics of arriving stimuli.
一种构建混洗自相关函数的方法被用于表征草蛙（林蛙）耳蜗核中的单个神经元。由重复的低频噪声片段调制的连续特征频率音调被用作刺激。该函数被计算为不同重复低频噪声片段诱发的放电之间的相关性。这种方法可以排除不应期的影响，并且还大大增加了代表性。将混洗自相关函数与传统自相关函数进行比较，可以估计神经元峰后兴奋性变化的时间动态。对几个例子的分析表明，在一些紧张性神经元的绝对不应期之后存在易化的可能性。仅对未调制的语音频率片段的起始表现出相位响应的神经元能够选择性地对噪声幅度调制的特殊时刻做出反应。这些细胞表现出极高的反应同步性。在青蛙的耳蜗核中，我们描述了一种具有放电内部周期性的神经元，它与传入刺激的动态无关。
