Jesorka Aldo, Orwar Owe
Department of Chemical and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden.
Methods Enzymol. 2009;464:309-25. doi: 10.1016/S0076-6879(09)64015-5.
Surfactant nanotube-vesicle networks (NVN) belong to the smallest artificial devices known to date for performing controlled chemical operations with enzymes. Newly established means for transport of chemical reactants between containers, as well as advancements in initiation and control of chemical reactions in such systems have opened pathways to new devices with a resolution down to the single-molecule level. Here, we summarize the fabrication and functionalization of complex nanotube-liposome networks for such devices, and discuss related aspects of their application for studying chemical kinetics and materials transport phenomena in ultrasmall-scale biomimetic environments.
表面活性剂纳米管 - 囊泡网络（NVN）属于迄今为止已知的用于对酶进行可控化学操作的最小人工装置。新建立的在容器之间传输化学反应物的方法，以及此类系统中化学反应引发和控制方面的进展，为分辨率低至单分子水平的新装置开辟了道路。在此，我们总结了用于此类装置的复杂纳米管 - 脂质体网络的制造和功能化，并讨论了它们在超小尺度仿生环境中研究化学动力学和材料传输现象的相关应用方面。
