Division of Colorectal Surgery, School of Medicine, University of São Paulo, São Paulo, Brazil.
Colorectal Dis. 2011 Mar;13(3):317-22. doi: 10.1111/j.1463-1318.2009.02128.x.
Chagas' disease is an endemic parasitosis found in Latin America. The disease affects different organs, such as heart, oesophagus, colon and rectum. Megacolon is the most frequent long-term complication, caused by damage to the myoenteric and submucous plexus, ultimately leading to a functional barrier to the faeces. Patients with severe constipation are managed surgically. The study aimed to analyse the 10-year minimum functional outcome after rectosigmoidectomy with posterior end-to-side anastomosis (RPESA).
A total of 21 of 46 patients were available for follow up. Patients underwent clinical, radiological and manometric evaluation, and the results were compared with preoperative parameters.
Of the 21 patients evaluated, 81% (17) were female, with a mean age of 60.6 years. Good function was achieved in all patients, with significant improvement in defaecatory frequency (P < 0.0001), usage of enemas (P < 0.0001) and patient satisfaction. Barium enema also showed resolution of the colonic and rectal dilatation in 19 cases evaluated postoperatively.
Minimal 10-year follow up of RPESA showed excellent functional results, with no recurrence of constipation.
恰加斯病是拉丁美洲流行的寄生虫病。该病可影响不同的器官,如心脏、食道、结肠和直肠。巨结肠是最常见的长期并发症,由肌间和黏膜下丛损伤引起,最终导致粪便功能障碍。严重便秘的患者需要手术治疗。本研究旨在分析经后路端端吻合直肠乙状结肠切除术(RPESA)后 10 年的最低功能结果。
46 例患者中共有 21 例可进行随访。对患者进行临床、放射学和测压评估,并将结果与术前参数进行比较。
21 例评估患者中,81%(17 例)为女性,平均年龄为 60.6 岁。所有患者均获得良好的功能,排便频率(P < 0.0001)、灌肠使用(P < 0.0001)和患者满意度均显著改善。19 例术后钡剂灌肠显示结肠和直肠扩张得到缓解。
RPESA 至少 10 年的随访结果显示出良好的功能效果,无便秘复发。