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贫血控制:来自面粉强化计划的经验教训。

Anaemia control: lessons from the flour fortification programme.

机构信息

Institute for Health Sciences Research, Academic Centre for Education, Culture and Research, P.O. Box 13145-483, Tehran, Iran.

出版信息

Public Health. 2009 Dec;123(12):794-9. doi: 10.1016/j.puhe.2009.09.024. Epub 2009 Nov 14.

Abstract

OBJECTIVES

Anaemia is an important public health problem in Iran; therefore, a programme of flour fortification with iron was launched in two pilot provinces. The present study was conducted in January 2009 to evaluate the effectiveness and process of this programme.

STUDY DESIGN

A 'before-and-after study' was conducted to evaluate the effectiveness of the flour fortification programme, and the process of the programme was evaluated using a cross-sectional study.

METHODS

To evaluate the effectiveness of the programme, blood haemoglobin and ferritin levels were measured in sample populations from Bushehr and Golestan provinces. The target population was women aged 15-49 years. Iron content was measured in samples of flour and bread to evaluate the flour fortification process in these two national pilot provinces.

RESULTS

The total study population was 600 women from Bushehr province and 652 women from Golestan province. Similar trends were found in the indicators of anaemia/iron deficiency among the women studied in both provinces. The flour fortification programme only appears to have had a beneficial effect on ferritin levels (iron deficiency) in the two provinces. The prevalence of iron-deficiency anaemia before and after the intervention did not differ significantly in either province. Interestingly, the prevalence of anaemia (low haemoglobin) was significantly higher after the intervention in women from both provinces. The coverage of fortified flour and bread was 90% and 98.7% in Bushehr province, and 94.1% and 95% in Golestan province, respectively.

CONCLUSIONS

In areas where anaemia is not mainly due to iron deficiency, an iron fortification programme might decrease the prevalence of iron deficiency without affecting the prevalence of anaemia.

摘要

目的

贫血是伊朗一个重要的公共卫生问题;因此,在两个试点省份启动了一项面粉铁强化计划。本研究于 2009 年 1 月进行,旨在评估该计划的有效性和进程。

研究设计

采用前后对照研究评估面粉强化计划的有效性,并采用横断面研究评估该计划的进程。

方法

为评估该计划的有效性,在布什尔省和戈勒斯坦省的抽样人群中测量了血液血红蛋白和铁蛋白水平。目标人群为 15-49 岁的妇女。为评估这两个国家试点省份的面粉强化过程,测量了面粉和面包中的铁含量。

结果

布什尔省共有 600 名妇女和戈勒斯坦省共有 652 名妇女参加了这项研究。这两个省份的研究对象中,贫血/缺铁的指标均呈现出相似的趋势。面粉强化计划似乎仅对这两个省份的铁蛋白水平(缺铁)产生了有益影响。干预前后,两省缺铁性贫血的患病率没有显著差异。有趣的是,干预后两省妇女贫血(低血红蛋白)的患病率显著升高。布什尔省强化面粉和面包的覆盖率分别为 90%和 98.7%,戈勒斯坦省分别为 94.1%和 95%。

结论

在贫血主要不是由缺铁引起的地区,铁强化计划可能会降低缺铁的患病率,而不会影响贫血的患病率。

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