Jones Elizabeth A, Phan Trinh D, Blanchard Deborah A, Miley Abbe
Cancer Services, Department of Nuclear Medicine, Legacy Good Samaritan Hospital, Portland, Oregon 97210, USA.
J Nucl Med Technol. 2009 Dec;37(4):201-5. doi: 10.2967/jnmt.109.063537. Epub 2009 Nov 13.
Breast-specific gamma-imaging (BSGI), also known as molecular breast imaging, is breast scintigraphy using a small-field-of-view gamma-camera and (99m)Tc-sestamibi. There are many different types of breast cancer, and many have characteristics making them challenging to detect by mammography and ultrasound. BSGI is a cost-effective, highly sensitive and specific technique that complements other imaging modalities currently being used to identify malignant lesions in the breast. Using the current Society of Nuclear Medicine guidelines for breast scintigraphy, Legacy Good Samaritan Hospital began conducting BSGI, breast scintigraphy with a breast-optimized gamma-camera. In our experience, optimal imaging has been conducted in the Breast Center by a nuclear medicine technologist. In addition, the breast radiologists read the BSGI images in correlation with the mammograms, ultrasounds, and other imaging studies performed. By modifying the current Society of Nuclear Medicine protocol to adapt it to the practice of breast scintigraphy with these new systems and by providing image interpretation in conjunction with the other breast imaging studies, our center has found BSGI to be a valuable adjunctive procedure in the diagnosis of breast cancer. The development of a small-field-of-view gamma-camera, designed to optimize breast imaging, has resulted in improved detection capabilities, particularly for lesions less than 1 cm. Our experience with this procedure has proven to aid in the clinical work-up of many of our breast patients. After reading this article, the reader should understand the history of breast scintigraphy, the pharmaceutical used, patient preparation and positioning, imaging protocol guidelines, clinical indications, and the role of breast scintigraphy in breast cancer diagnosis.
乳腺特异性γ成像（BSGI），也称为分子乳腺成像，是一种使用小视野γ相机和（99m）锝-甲氧基异丁基异腈的乳腺闪烁扫描术。乳腺癌有许多不同类型，其中许多具有一些特征，使得通过乳房X线摄影和超声检测它们具有挑战性。BSGI是一种经济高效、高度敏感且特异的技术，可补充目前用于识别乳腺恶性病变的其他成像方式。根据核医学协会目前关于乳腺闪烁扫描术的指南，遗产好撒玛利亚医院开始进行BSGI，即使用乳腺优化γ相机的乳腺闪烁扫描术。根据我们的经验，乳腺中心的核医学技术人员进行了最佳成像。此外，乳腺放射科医生会结合乳房X线照片、超声检查及其他进行的成像研究来解读BSGI图像。通过修改核医学协会目前的方案，使其适应使用这些新系统进行乳腺闪烁扫描术的实践，并结合其他乳腺成像研究提供图像解读，我们中心发现BSGI在乳腺癌诊断中是一种有价值的辅助检查方法。一种旨在优化乳腺成像的小视野γ相机的开发，提高了检测能力，尤其是对于小于1厘米的病变。我们在这个检查方法上的经验已证明有助于对我们许多乳腺疾病患者进行临床检查。阅读本文后，读者应了解乳腺闪烁扫描术的历史、所用药物、患者准备和定位、成像方案指南、临床适应症以及乳腺闪烁扫描术在乳腺癌诊断中的作用。
