Children's University Hospital Zagreb, Klaićeva, Zagreb, Croatia.
Reprod Toxicol. 2010 Apr;29(2):237-41. doi: 10.1016/j.reprotox.2009.11.006. Epub 2009 Nov 13.
We present the results of active case ascertainment of fetal alcohol syndrome (FAS). This study included a sample of urban schoolchildren attending 1st to 4th grade elementary school and their mothers. Out of 912 mothers, 575 (63.04%) participated in the interview. Prenatal alcohol consumption was admitted by 15.47% and binge drinking by 3.13% of interviewed mothers. We evaluated 466 (51.09%) schoolchildren for signs of FAS or partial fetal alcohol syndrome (PFAS) using revised Institute of Medicine (IOM) diagnostic criteria. Nineteen students had features consistent with FAS or PFAS. The observed prevalence of FAS is 3 children and of PFAS is 16 children among 466 students, based on 51% participation rate. The estimated prevalence of FAS is 6.44/1000, of PFAS 34.33/1000 and overall prevalence of FAS/PFAS 40.77/1000. This is the first study of FAS prevalence in Croatia and as far as we are aware the second study in Europe.
我们呈现了胎儿酒精综合征(FAS)主动病例确定的结果。这项研究包括了一组城市小学生的样本,他们正在上 1 到 4 年级,以及他们的母亲。在 912 位母亲中,有 575 位(63.04%)参与了访谈。接受访谈的母亲中,有 15.47%承认在怀孕期间饮酒,3.13%承认狂饮。我们使用修订后的医学研究所(IOM)诊断标准,对 466 位(51.09%)小学生进行了 FAS 或部分胎儿酒精综合征(PFAS)的体征评估。19 位学生具有符合 FAS 或 PFAS 的特征。根据 51%的参与率,在 466 位学生中,有 3 位患有 FAS,16 位患有 PFAS。FAS 的估计患病率为 6.44/1000,PFAS 为 34.33/1000,FAS/PFAS 的总患病率为 40.77/1000。这是克罗地亚首次对 FAS 患病率进行的研究,据我们所知,这也是欧洲的第二项研究。