Koning J P, Tenback D E, Kahn R S, Van Schelven L J, Van Harten P N
Psychiatric Centre Symfora Group, Utrechtseweg 266, Amersfoort, 3800 DB, The Netherlands.
J Med Eng Technol. 2010 Jan;34(1):71-7. doi: 10.3109/03091900903402105.
Tardive tongue dyskinesia is often under-diagnosed or misdiagnosed. Instrument measurement of lingual force variability may be a valid and reliable method for assessing tardive tongue dyskinesia. Instrument measurement of lingual force variability was compared to the clinical level of tardive tongue dyskinesia and total body dyskinesia as measured by the Abnormal Involuntary Movement Scale (AIMS) in 35 subjects: 23 patients with a psychiatric disorder using antipsychotics, of which 11 were with and 12 were without tardive tongue dyskinesia, and 12 age- and gender-matched healthy controls. Lingual force variability correlated with tardive tongue dyskinesia (Spearman r = 0.56; p < 0.01) and with total dyskinesia (r = 0.47; p = 0.02); there was no association with age, antipsychotic dose, or psychiatric diagnosis. Instrument test-retest reliability corresponded with an ICC of 0.85 p < 0.0001. Instrument measurement of lingual force variability is a valid and reliable method for assessing tardive tongue dyskinesia.
迟发性舌运动障碍常常诊断不足或误诊。舌力变异性的仪器测量可能是评估迟发性舌运动障碍的一种有效且可靠的方法。在35名受试者中，将舌力变异性的仪器测量结果与通过异常不自主运动量表（AIMS）测量的迟发性舌运动障碍和全身运动障碍的临床水平进行了比较：23名使用抗精神病药物的精神疾病患者，其中11名患有迟发性舌运动障碍，12名未患迟发性舌运动障碍，以及12名年龄和性别匹配的健康对照者。舌力变异性与迟发性舌运动障碍相关（斯皮尔曼r = 0.56；p < 0.01），与全身运动障碍相关（r = 0.47；p = 0.02）；与年龄、抗精神病药物剂量或精神疾病诊断无关。仪器重测信度的组内相关系数（ICC）为0.85，p < 0.0001。舌力变异性的仪器测量是评估迟发性舌运动障碍的一种有效且可靠的方法。
