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经皮肺动脉瓣植入术

Percutaneous pulmonic valve implantation.

作者信息

Kumar Arun, Kavinsky Clifford, Amin Zahid, Hijazi Ziyad M

机构信息

Rush Center for Congenital and Structural Heart Disease, Rush University Medical Center, 1653 West Congress Parkway, Jones 770, Chicago, IL 60612, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2009 Dec;11(6):483-91. doi: 10.1007/s11936-009-0051-3.

Abstract

Surgically placed valve conduits between the right ventricle and pulmonary artery often fail within 10 years. The failure may be the result of insufficiency, stenosis, or often a combination of the two. Pulmonic valve insufficiency may lead to right ventricular dilatation, heart failure, arrhythmias, and death. Reoperation requires cardiopulmonary bypass, which may aggravate an already failing right ventricle, and is associated with a higher risk of death and significant morbidity. Therefore, percutaneous implantation of a pulmonic valve is an attractive option to improve hemodynamic function and ameliorate symptoms. Initial experience with various types of percutaneous pulmonary valve systems demonstrates the procedure to be effective and safe. Improvements in technique and device modification are evolving rapidly. Studies and clinical follow-up are ongoing to further assess functional improvement, freedom from adverse cardiac events, and longevity of percutaneously implanted valves.

摘要

手术植入的右心室与肺动脉之间的瓣膜管道通常在10年内失效。失效可能是由于瓣膜关闭不全、狭窄,或通常是两者兼而有之。肺动脉瓣关闭不全可能导致右心室扩张、心力衰竭、心律失常和死亡。再次手术需要体外循环,这可能会加重本已衰竭的右心室负担,并伴有更高的死亡风险和显著的发病率。因此,经皮植入肺动脉瓣是改善血流动力学功能和缓解症状的一个有吸引力的选择。各种类型经皮肺动脉瓣系统的初步经验表明该手术是有效且安全的。技术改进和器械改良正在迅速发展。正在进行研究和临床随访,以进一步评估经皮植入瓣膜后的功能改善情况、无不良心脏事件的发生率以及使用寿命。

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