E. Kenneth Hatton, MD, Institute for Research and Education, Good Samaritan Hospital, 375 Dixmyth Ave, Cincinnati, OH 45220, USA.
Ann Thorac Surg. 2009 Dec;88(6):1793-800. doi: 10.1016/j.athoracsur.2009.07.077.
More than one third of adults in the United States are obese. Coronary artery bypass graft surgery (CABG) has become necessary for many obese persons. We evaluated the effect of this procedure on in-hospital mortality and morbidity of patients based on their body mass index (BMI).
Data in a cardiac surgery database were examined retrospectively. Data selected from the database included CABG surgery from January 2003 to December 2007. The resulting cohort included a total of 10,590 patients. The BMI was grouped into four categories: underweight (BMI < or = 19), normal weight (BMI 20 to 29), obese (BMI 30 to 39), and morbidly obese (BMI > or = 40). Regression analysis was conducted to determine whether BMI was an independent predictor of morbidity and mortality after CABG.
Our results indicate that patients with an obese BMI are not at greater risk for morbidity or mortality after CABG. Logistic regression analysis found that CABG patients in the underweight body mass index group had the greatest risk of mortality, prolonged ventilation, reoperation for bleeding, and renal failure. Linear regression indicated length of hospital stay and intensive care unit stay after surgery were the longest for patients with an underweight BMI.
Despite the comorbidities that are often present with obesity, an obese BMI was not found to be an independent predictor of morbidity or mortality after CABG. On the contrary, the underweight patients are at greater risk for mortality and complications after CABG surgery.
美国超过三分之一的成年人肥胖。许多肥胖者需要进行冠状动脉旁路移植手术(CABG)。我们根据体重指数(BMI)评估了该手术对住院死亡率和发病率的影响。
回顾性检查心脏手术数据库中的数据。从数据库中选择的数据包括 2003 年 1 月至 2007 年 12 月期间的 CABG 手术。共纳入 10590 例患者。BMI 分为四组:体重不足(BMI ≤ 19)、正常体重(BMI 20-29)、肥胖(BMI 30-39)和病态肥胖(BMI ≥ 40)。进行回归分析以确定 BMI 是否是 CABG 后发病率和死亡率的独立预测因子。
我们的结果表明,肥胖 BMI 的患者在 CABG 后发病率或死亡率没有增加的风险。逻辑回归分析发现,体重不足组的 CABG 患者死亡率最高,需要长时间通气、再次因出血而手术以及发生肾衰竭。线性回归表明,体重不足的患者手术后的住院时间和重症监护病房的住院时间最长。
尽管肥胖常伴有合并症,但肥胖 BMI 并不是 CABG 后发病率或死亡率的独立预测因子。相反,体重不足的患者在 CABG 手术后死亡率和并发症的风险更高。