Department of Neurology & Psychiatry, Saint Louis University School of Medicine, 1438 South Grand Boulevard, St Louis, MO 63104, USA.
Neurol Clin. 2010 Feb;28(1):293-309. doi: 10.1016/j.ncl.2009.09.013.
Fungal infections of the central nervous system (CNS) have a high rate of morbidity and mortality caused by several factors. Most importantly, the last three decades have witnessed a rising prevalence of susceptible hosts from the growing numbers of organ transplants, chemotherapy patients, and intensive care unit hospitalizations. Knowledge of CNS fungal infections including their symptoms and signs, required diagnostic studies, and treatment methods is imperative for all neurologists. This article provides an overview of the clinical features and laboratory findings of the major mycoses affecting the CNS and a focus on their neurologic presentations.
中枢神经系统(CNS)真菌感染由多种因素导致发病率和死亡率高。最重要的是,过去三十年中,由于器官移植、化疗患者和重症监护病房住院人数的增加,易感宿主的数量不断增加。所有神经科医生都必须了解 CNS 真菌感染,包括其症状和体征、所需的诊断研究以及治疗方法。本文概述了影响 CNS 的主要真菌病的临床特征和实验室发现,并重点介绍了它们的神经表现。