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[家蚕微孢子虫两个分离株的致病性与遗传差异]

[Pathogenicity and genetic divergence of two isolates of microsporidia Nosema bombycis].

作者信息

WANG Min, XU Jin-Shan, WANG Lin-Ling, ZHANG Xiao-Yan, ZHOU Ze-Yang

机构信息

Laboratory of Animal Biology, Chongqing Normal University, Chongqing 400047, China.

出版信息

Yi Chuan. 2009 Nov;31(11):1121-6. doi: 10.3724/sp.j.1005.2009.01121.

Abstract

Microsporidia Nosema bombycis is a fungal pathogen that causes epidemic pebrine disease in Bombyx mori. Two N. bombycis isolates were obtained from two areas in China and showed different pathogenicity after Spodoptera frugiperda Sf9 cell cultivation. The regions of rDNAs from different isolates were analyzed, suggesting no relationship between the genetic divergence and their geographic distributions. Further analysis showed that several copies of SSU rDNA units in N. bombycis were interrupted by a MITE-like transposon, indicating the complexity of genomic structure in Nosema bombycis.

摘要

微孢子虫家蚕微孢子虫是一种真菌病原体,可在家蚕中引发流行性脓病。从中国的两个地区获得了两株家蚕微孢子虫分离株,它们在草地贪夜蛾Sf9细胞培养后表现出不同的致病性。对不同分离株的rDNA区域进行了分析,结果表明遗传差异与其地理分布之间没有关系。进一步分析表明,家蚕微孢子虫中的几个SSU rDNA单位拷贝被一个类MITE转座子打断,这表明家蚕微孢子虫基因组结构的复杂性。

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