Katzman S S, Johnston J O
Department of Orthopaedic Surgery, University of Arizona Health Sciences Center, Tucson 85724.
Clin Orthop Relat Res. 1991 Feb(263):227-32.
This epidemiologic study represents an analysis of all registered new cases of osteogenic sarcoma (OGS) during the 14-year period from January 1973 to December 1986 in five San Francisco Bay counties. Inclusion into the study was limited to patients who were diagnosed in the first three decades of life and who were residents within the Bay Area at the time of diagnosis. To determine epidemiologic characteristics of OGS, records on 96 patients from the Bay Area Resources for Cancer Control with histologically proven OGS were reviewed. The incidence of OGS was influenced by age, gender, and race, but none of the effects were statistically significant. A geographic variation in the incidence of OGS was discovered, although it was not statistically significant. The results are presented in support of a continued search for environmental variables that may someday reveal the etiologic factors of OGS.
这项流行病学研究对1973年1月至1986年12月这14年间旧金山湾区五个县所有登记在册的骨肉瘤新发病例进行了分析。纳入该研究的仅限于在生命的头三十年被诊断出且在诊断时为湾区居民的患者。为了确定骨肉瘤的流行病学特征，对来自湾区癌症控制资源中心的96例经组织学证实为骨肉瘤的患者记录进行了审查。骨肉瘤的发病率受年龄、性别和种族的影响，但这些影响均无统计学意义。虽然骨肉瘤发病率的地理差异无统计学意义，但仍被发现。呈现这些结果是为了支持继续寻找可能有朝一日揭示骨肉瘤病因的环境变量。
