Huberman Andrew D
Department of Neurobiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
Neuron. 2009 Nov 25;64(4):441-3. doi: 10.1016/j.neuron.2009.11.011.
In this issue of Neuron, Fuerst et al., report that mammalian DSCAMs powerfully regulate the mosaic spacing of neurons in the retina, but not their synaptic specificity. The results unveil critical features regarding the type and scope of molecular interactions that guide neural circuit assembly in the mammalian CNS.
在本期《神经元》杂志中，富尔斯特等人报道，哺乳动物的唐氏综合征细胞黏附分子（DSCAMs）有力地调节视网膜中神经元的镶嵌间距，但不调节它们的突触特异性。这些结果揭示了有关指导哺乳动物中枢神经系统神经回路组装的分子相互作用的类型和范围的关键特征。
