两名颅咽管瘤治疗后患有下丘脑性肥胖的青少年接受减肥手术后的结果。
Outcome after bariatric surgery in two adolescents with hypothalamic obesity following treatment of craniopharyngioma.
作者信息
Rottembourg Diane, O'Gorman Clodagh S, Urbach Stacey, Garneau Pierre Y, Langer Jacob C, Van Vliet Guy, Hamilton Jill, Huot Céline
机构信息
Department of Pediatrics, Divisions of Endocrinology, CHU Sainte-Justine, Université de Montréal, Montreal, PQ, Canada.
出版信息
J Pediatr Endocrinol Metab. 2009 Sep;22(9):867-72. doi: 10.1515/jpem.2009.22.9.867.
Treatment of craniopharyngioma (CP) in childhood can lead to severe, debilitating obesity with devastating medical and psychological outcomes. Despite sustained nutritional and exercise-oriented interventions, no efficacious medical option is available for hypothalamic obesity. We describe two adolescents who developed morbid obesity and significant comorbidities following diagnosis and treatment of CP, in whom bariatric surgery was achieved, illustrating a novel approach for symptomatic hypothalamic obesity, as well as positive and negative outcomes.
儿童颅咽管瘤（CP）的治疗可能导致严重的、使人衰弱的肥胖症，并产生毁灭性的医学和心理后果。尽管采取了持续的以营养和运动为导向的干预措施，但对于下丘脑性肥胖症，尚无有效的医学治疗方法。我们描述了两名青少年，他们在被诊断和治疗CP后出现了病态肥胖和严重的合并症，接受了减肥手术，这说明了一种针对症状性下丘脑性肥胖症的新方法，以及其积极和消极的结果。
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