Tian Bo-Le, Zhang Zhao-Da, Liu Xu-Bao, Hu Wei-Ming, Mai Gang, Zeng Yong, Li Zhen-Jun, Zhang Yi, Le Xin-Hui, Lu Hui-Min
Department of Hepato-bilio-pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhonghua Wai Ke Za Zhi. 2009 Jun 1;47(11):814-7.
To explore the value of the POSSUM scoring system in predicting postoperative morbidity and mortality of pancreatoduodenectomy (PD).
Two hundreds and sixty-five consecutive PDs were performed between January 2005 and December 2007. POSSUM scores which relied on 12 physiologic and 6 operative variables were prospectively calculated for each case. Expected morbidity and mortality were estimated based on POSSUM scores and were compared with observed morbidity, which were diagnosed according to the Clavien complication scheme and domestic reference criteria respectively, and mortality.
Physiologic scores of 265 cases ranged from 12 to 24,the mean was 15. Operative scores ranged from 14 to 24, the mean was 17. The overall POSSUM scores ranged from 0.24 to 0.88. Average expected morbidity was 43.8%, expected cases were 116. Observed morbidity rate was 39.6% (105/265). The expected and observed morbidities and cases had no significantly differences. All patients were classified to 1 of 4 strata based on their individual POSSUM scores and subsequent risk of morbidity. Predictive value was the highest when scores ranged from 0.4 to 0.8. POSSUM exhibited less predictive value for mortality, but if POSSUM was more than 0.5, it was useful for mortality predicting.
POSSUM scoring system has high value for predicting the risk of morbidity in PD and can be helpful in guiding surgery and postoperative management decisions.
探讨POSSUM评分系统在预测胰十二指肠切除术(PD)术后发病率和死亡率方面的价值。
2005年1月至2007年12月期间连续进行了265例PD手术。前瞻性地为每例患者计算基于12项生理变量和6项手术变量的POSSUM评分。根据POSSUM评分估计预期发病率和死亡率,并与分别根据Clavien并发症方案和国内参考标准诊断的观察到的发病率及死亡率进行比较。
265例患者的生理评分范围为12至24分,平均为15分。手术评分范围为14至24分,平均为17分。总体POSSUM评分范围为0.24至0.88。平均预期发病率为43.8%,预期病例数为116例。观察到的发病率为39.6%(105/265)。预期发病率与观察到的发病率及病例数无显著差异。根据患者个体的POSSUM评分及其随后的发病风险,将所有患者分为4个分层中的1个。当评分范围为0.4至0.8时,预测价值最高。POSSUM对死亡率的预测价值较低,但如果POSSUM大于0.5,则对死亡率预测有用。
POSSUM评分系统在预测PD发病风险方面具有较高价值,有助于指导手术及术后管理决策。