Intensive Care Unit, Hospital Virgen de la Salud, Toledo, Madrid, Spain.
Respir Care. 2009 Dec;54(12):1644-52.
To determine the relationship between tracheostomy tube in place after intensive-care-unit (ICU) discharge and hospital mortality.
We conducted a prospective observational cohort study in a medical-surgical ICU in a tertiary-care hospital that does not have a step-down unit. We recorded clinical and epidemiologic variables, indication and timing of tracheostomy, time to decannulation, characteristics of respiratory secretions, need for suctioning, and Glasgow coma score at ICU discharge. We excluded patients who had do-not-resuscitate orders, tracheostomy for long-term airway control, neuromuscular disease, or neurological damage.
A total of 118 patients were tracheostomized in the ICU, and 73 were discharged to the ward without neurological damage. Of these, 35 had been decannulated. Ward mortality was 19% overall, 11% in decannulated patients, and 26% in patients with the tracheostomy tube in place; that difference was not statistically significant in the univariate analysis (P = .10). However, the multivariate analysis, which adjusted for lack of decannulation, age, sex, body mass index, severity of illness, diagnosis at ICU admission, duration of mechanical ventilation, Glasgow coma score, characteristics of respiratory secretions, and need for suctioning at ICU discharge, found 3 factors associated with ward mortality: lack of decannulation at ICU discharge (odds ratio 6.76, 95% confidence interval 1.21-38.46, P = .03), body mass index > 30 kg/m(2) (odds ratio 5.81, 95% confidence interval 1.24-27.24, P = .03), and tenacious sputum at ICU discharge (odds ratio 7.27, 95% confidence interval 1-55.46, P = .05).
In our critical-care setting, lack of decannulation of conscious tracheostomized patients before ICU discharge to the general ward was associated with higher mortality.
确定重症监护病房(ICU)出院后带管与院内死亡率之间的关系。
我们在一家三级医院的内科-外科 ICU 进行了一项前瞻性观察队列研究,该医院没有下病房。我们记录了临床和流行病学变量、气管切开术的指征和时机、拔管时间、呼吸分泌物的特征、吸痰的需要以及 ICU 出院时的格拉斯哥昏迷评分。我们排除了有不复苏医嘱、长期气道控制、神经肌肉疾病或神经损伤的气管切开术患者。
共有 118 例患者在 ICU 行气管切开术,其中 73 例无神经损伤出院至病房。其中 35 例已拔管。总体病死率为 19%,拔管患者为 11%,带管患者为 26%;在单因素分析中,差异无统计学意义(P=.10)。然而,多变量分析,调整了未拔管、年龄、性别、体重指数、疾病严重程度、ICU 入院诊断、机械通气时间、格拉斯哥昏迷评分、ICU 出院时呼吸分泌物的特征和吸痰的需要,发现有 3 个因素与病房死亡率相关:ICU 出院时未拔管(比值比 6.76,95%置信区间 1.21-38.46,P=.03)、体重指数>30kg/m²(比值比 5.81,95%置信区间 1.24-27.24,P=.03)和 ICU 出院时痰液粘稠(比值比 7.27,95%置信区间 1-55.46,P=.05)。
在我们的重症监护环境中,意识清醒的气管切开术患者在 ICU 出院到普通病房前未拔管与更高的死亡率相关。