Faculty of Pharmacy, Rhodes University, Grahamstown, 6140, Eastern Cape, South Africa.
Res Social Adm Pharm. 2009 Dec;5(4):363-75. doi: 10.1016/j.sapharm.2009.01.004.
The burden of chronic noncommunicable diseases continues to rise in South Africa, leading to high rates of morbidity and mortality. The control of hypertension is far from optimal because of factors such as inadequate patient understanding of the condition and its therapy, as well as poor adherence to prescribed regimens.
This study investigated the effect of an educational intervention on selected hypertensive participants' levels of knowledge about hypertension, their beliefs about medicines, and adherence to antihypertensive therapy.
Participants took part in an educational intervention that provided them with information about hypertension and its therapy through presentations, monthly meetings, and a summary information leaflet. The participants' levels of knowledge about hypertension and its therapy as well as their beliefs about medicines were measured using interviews and/or self-administered questionnaires. Levels of adherence were assessed using pill counts, self-reports, and punctuality in collecting medication refills. Paired t tests for dependent samples were performed to compare the participants' levels of knowledge about hypertension and its therapy, beliefs about medicines, and levels of adherence to antihypertensive therapy before and after the educational intervention.
There were significant increases in the participants' levels of knowledge about hypertension and its therapy (P<.0001). Most of the parameters used to indicate beliefs about medicines were significantly modified in a positive manner (P<.01 for concerns about medicines, P<.01 for beliefs about the harmful nature of medicines, and P<.01 for the necessity-concerns differential).
Results of this study show that the educational intervention led to an increase in the participants' levels of knowledge about hypertension and a positive influence on their beliefs about medicines. Despite these positive changes, adequate time is required before anticipated behavioral changes, such as increased adherence, can be observed.
在南非,慢性非传染性疾病的负担持续增加,导致发病率和死亡率居高不下。由于患者对疾病及其治疗的理解不足,以及对规定治疗方案的依从性差等因素,高血压的控制远不理想。
本研究调查了教育干预对选定高血压患者对高血压的知识水平、对药物的信念以及对降压治疗的依从性的影响。
参与者参加了一项教育干预,通过演示、每月会议和一份摘要信息传单为他们提供有关高血压及其治疗的信息。通过访谈和/或自我管理问卷来测量参与者对高血压及其治疗的知识水平以及对药物的信念。通过药片计数、自我报告和按时领取药物补充剂来评估依从性水平。使用配对 t 检验对依赖样本进行比较,以比较教育干预前后参与者对高血压及其治疗、对药物的信念以及对降压治疗的依从性的知识水平。
参与者对高血压及其治疗的知识水平显著提高(P<.0001)。用于表示对药物的信念的大多数参数都以积极的方式显著改变(对药物的担忧 P<.01,对药物有害性的信念 P<.01,必要性-担忧差异 P<.01)。
本研究结果表明,教育干预导致参与者对高血压的知识水平提高,并对他们对药物的信念产生积极影响。尽管有这些积极的变化,但在预期的行为变化(如依从性增加)得到观察之前,还需要足够的时间。