[结直肠癌术后死亡风险因素：专科单位队列随访]

[Postoperative mortality risk factors in colorectal cancer: follow up of a cohort in a specialised unit].

作者信息

Errasti Alustiza José, Cermeño Toral Baltasar, Campo Cimarras Eugenia, Romeo Ramírez José Antonio, Sardón Ramos José Domingo, Reka Mediavilla Lorena, Arrillaga Alcorta Iratxe, Parraza Díez Naiara

机构信息

Servicio de Cirugía General, Hospital Txagorritxu, Vitoria-Gasteiz, España.

出版信息

Cir Esp. 2010 Feb;87(2):101-7. doi: 10.1016/j.ciresp.2009.09.012. Epub 2009 Dec 5.

DOI:10.1016/j.ciresp.2009.09.012

PMID:19963211

Abstract

INTRODUCTION

The treatment of colorectal cancer (CRC) is usually surgical and involves morbidity-mortality. The aim of this study is to quantify the postoperative mortality in our hospital and to determine their risk factors.

MATERIALS AND METHODS

Prospective observational study from 1996 to 2007 included 1017 patients who underwent surgery for CRC in our hospital. Identification of independent risk factors for postoperative mortality by multivariate analysis.

RESULTS

The mean age was 67.8 years. The surgery was elective in 879 (86.5%) and was considered curative in 878 (86.1%). The postoperative mortality was 3.6% (37 patients), 2.5% in the elective surgery and 10.9% in the urgent. The independent risk factors identified were: type of surgery (odds ratio for urgent vs. elective=2.8), American Society of Anesthesiologists (ASA) grade (odds ratio for ASA III-IV vs. I-II=2.4), age (odds ratio for age > or = 85 vs. < or = 74=7.6 and age 75-84 vs. < or = 74=2.4).

CONCLUSIONS

We found a low postoperative mortality, which was mainly associated with age over 75 years, ASA III or IV stages and urgent surgery.

摘要

引言

结直肠癌（CRC）的治疗通常采用手术方式，且存在发病和死亡风险。本研究旨在量化我院的术后死亡率，并确定其风险因素。

材料与方法

对1996年至2007年的前瞻性观察性研究纳入了我院1017例行CRC手术的患者。通过多变量分析确定术后死亡的独立风险因素。

结果

平均年龄为67.8岁。879例（86.5%）手术为择期手术，878例（86.1%）被认为是根治性手术。术后死亡率为3.6%（37例患者），择期手术中为2.5%，急诊手术中为10.9%。确定的独立风险因素为：手术类型（急诊手术与择期手术的比值比=2.8）、美国麻醉医师协会（ASA）分级（ASA III-IV级与I-II级的比值比=2.4）、年龄（年龄≥85岁与≤74岁的比值比=7.6，年龄75-84岁与≤74岁的比值比=2.4）。