利用呼吸系统的音频传递函数检测肺部区域特性。

Detecting regional lung properties using audio transfer functions of the respiratory system.

作者信息

Mulligan K, Adler A, Goubran R

机构信息

Department of Systems and Computer Engineering, Carleton University, Ottawa, Ontario, Canada.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:5697-700. doi: 10.1109/IEMBS.2009.5333107.

DOI:10.1109/IEMBS.2009.5333107

PMID:19963910

Abstract

In this study, a novel instrument has been developed for measuring changes in the distribution of lung fluid the respiratory system. The instrument consists of a speaker that inputs a 0-4kHz White Gaussian Noise (WGN) signal into a patient's mouth and an array of 4 electronic stethoscopes, linked via a fully adjustable harness, used to recover signals on the chest surface. The software system for processing the data utilizes the principles of adaptive filtering in order to obtain a transfer function that represents the input-output relationship for the signal as the volume of fluid in the lungs is varied. A chest phantom model was constructed to simulate the behavior of fluid related diseases within the lungs through the injection of varying volumes of water. Tests from the phantom model were compared to healthy subjects. Results show the instrument can obtain similar transfer functions and sound propagation delays between both human and phantom chests.

摘要

在本研究中，已开发出一种新型仪器，用于测量呼吸系统中肺液分布的变化。该仪器由一个向患者口腔输入0-4kHz白高斯噪声（WGN）信号的扬声器和通过完全可调节背带连接的4个电子听诊器阵列组成，用于采集胸部表面的信号。处理数据的软件系统利用自适应滤波原理，以获得一个传递函数，该传递函数表示随着肺内液体量的变化，信号的输入-输出关系。构建了一个胸部体模模型，通过注入不同体积的水来模拟肺部与液体相关疾病的行为。将体模模型的测试结果与健康受试者进行了比较。结果表明，该仪器能够在人体胸部和体模胸部之间获得相似的传递函数和声传播延迟。