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不透明角膜的角膜移植术

Corneal Transplantation on an Opaque Cornea.

作者信息

Thomas J W

出版信息

Proc R Soc Med. 1933 Mar;26(5):597-605. doi: 10.1177/003591573302600567.

Abstract

A man, aged 22, had opacity of both corneae, following severe interstitial keratitis at the age of 18. Vision reduced to that of hand movements.Corneal transplantation performed on left eye in November 1930. The graft was taken from an eye removed one month after a perforating injury. Operation performed under cocaine anaesthesia, using the technique established experimentally in rabbits, with the addition of a glass disc interposed between the graft and the overlying stitches. The graft was slightly smaller than the piece of opaque cornea removed, and the margins of each were cut shelving.-The stitches and glass disc were removed on the tenth day; the graft had united well and was nearly clear.-During the next week it began to get hazy, and some minute blood-vessels appeared in its stroma, so that vision deteriorated; a few weeks later it began to improve.Four months after operation patient could count fingers at 2 ft. Two years after operation he could count fingers up to 33 in. with the light behind him.

摘要

一名22岁男性,18岁时患严重间质性角膜炎后双眼角膜混浊。视力降至仅能手动。1930年11月对左眼进行了角膜移植。移植片取自穿孔伤后一个月摘除的眼球。手术在可卡因麻醉下进行,采用在兔子身上通过实验确立的技术,并在移植片与覆盖缝线之间插入一块玻璃盘。移植片比切除的不透明角膜片略小,二者边缘均切成斜面。第十天拆除缝线和玻璃盘;移植片愈合良好,几乎透明。在接下来的一周里,它开始变得模糊,基质中出现了一些微小血管,视力因此恶化;几周后又开始改善。术后四个月,患者在2英尺处能数指。术后两年,在光线从其身后照射时,他在33英寸处能数指。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f5/2204185/ad733cbc4d12/procrsmed00705-0108-a.jpg

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