胃肠道间质瘤与恶性上皮性肿瘤并存：两例报告。
Co-existence of gastrointestinal stromal tumors with malign epithelial tumors: a report of two cases.
作者信息
Firat O, Yazici P, Makay O, Aydin A, Tuncyurek M, Ersin S, Guler A
机构信息
Department of General Surgery, Ege University School of Medicine, Izmir, Turkey.
出版信息
Acta Chir Belg. 2009 Oct;109(5):629-32. doi: 10.1080/00015458.2009.11680502.
AIM
To emphasize the importance of a detailed observation for incidental simultaneous tumoral masses during surgery for gastrointestinal stromal tumors (GISTs) at any location in the gastrointestinal system.
CASE PRESENTATIONS
Case 1: a 39-year-old female patient with an esophageal squamous cell carcinoma and a synchronous small intestinal GIST discovered incidentally during esophagectomy. Case 2: a 73-year-old female patient with a gastric GIST and a synchronous colorectal cancer detected incidentally during gastrectomy. In both cases, immunohistochemical examinations of the resected specimens confirmed the coexistences of GISTs and epithelial malignancies.
CONCLUSION
The coexistences of GISTs with epithelial tumors have been increasing in recent years. In any case of a GIST or gastrointestinal adenocarcinoma, the surgeon should be alert to recognize a possible coexistent tumor with different histological origin.
目的
强调在胃肠道系统任何部位的胃肠道间质瘤（GIST）手术中，对偶然同时出现的肿瘤性肿块进行详细观察的重要性。
病例报告
病例1：一名39岁女性患者，在食管癌切除术中偶然发现患有食管鳞状细胞癌和同步性小肠GIST。病例2：一名73岁女性患者，在胃癌切除术中偶然检测到患有胃GIST和同步性结直肠癌。在这两个病例中，对切除标本进行的免疫组织化学检查证实了GIST和上皮性恶性肿瘤的共存。
结论
近年来，GIST与上皮性肿瘤的共存情况一直在增加。在任何GIST或胃肠道腺癌病例中，外科医生都应警惕识别可能存在的具有不同组织学起源的共存肿瘤。
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