早产预防:宫颈环扎术的作用。
Prematurity prevention: the role of cerclage.
机构信息
Division of Maternal-Fetal Medicine, First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, Athens University, Athens, Greece.
出版信息
Curr Opin Obstet Gynecol. 2009 Apr;21(2):148-52. doi: 10.1097/GCO.0b013e3283294785.
PURPOSE OF REVIEW
To summarize the literature on the value of cervical cerclage for the prevention of preterm birth and present the recent advances in its clinical application.
RECENT FINDINGS
The diagnosis of cervical insufficiency is difficult as there are no objective diagnostic criteria. Although widely used, the value of cervical cerclage is still a matter of controversy. The current literature suggests that cerclage placement can prevent preterm delivery in women with a history of at least three second-trimester losses or at least three preterm births and in those with a history of prematurity who have a cervical length of less than 25 mm in the second trimester. It is also possible to improve the perinatal outcome in patients with cervical dilation in the mid-trimester. It is not indicated in multiple pregnancies, however. Further research is needed in methods of excluding inflammation in women with cervical changes on ultrasound prior to cerclage insertion. Transabdominal or laparoscopic cerclage seems to be a promising alternative in women with a history of transvaginal cerclage failure.
SUMMARY
Strict recommendations on the proper use of cerclage cannot be easily made. Data from randomized trials do not support what the current practice in many cases is.
目的综述
总结宫颈环扎术预防早产的文献,并介绍其临床应用的最新进展。
最新发现
由于缺乏客观的诊断标准,宫颈机能不全的诊断较为困难。尽管宫颈环扎术应用广泛,但它的价值仍存在争议。目前的文献表明,对于既往至少有 3 次中孕期流产或至少有 3 次早产史,或既往有早产史且中孕期宫颈长度<25mm 的患者,环扎术可预防早产。对于中孕期宫颈扩张的患者,也可能改善围产期结局。但对于多胎妊娠则不适用。对于在宫颈环扎术前超声检查发现宫颈变化的患者,需要进一步研究排除炎症的方法。对于既往经阴道宫颈环扎术失败的患者,经腹或腹腔镜宫颈环扎术似乎是一种有前途的替代方法。
总结
对于宫颈环扎术的正确使用,不能轻易做出严格的建议。随机试验的数据并不支持目前许多情况下的实际做法。