Erdenen Füsun, Altungolu Esma, Boz Mustafa, Celik Serap, Ozbal Nurcan, Lehners Christiane, Hentges François
Ministry of Health Istanbul Training and Research Hospital, Istanbul.
Bull Soc Sci Med Grand Duche Luxemb. 2009(2):135-40.
The goal of this study was to investigate a possible relationship between allergic symptoms, atopy skin prick test results in type 1 diabetic patients and in non diabetic controls.
50 type 1 diabetic patients and 50 healthy control subjects were evaluated for allergic disorders with regard to medical history. All persons were skin-prick-tested for atopic sensitization with a common panel of inhalant and food allergens.
Although in the diabetic group 56% of the patients reported allergy-like respiratory symptoms, only 22% were found to have positive skin tests. In the control group 22% had allergic complaints and skin prick tests were positive in 34% of the cases.
Nasal and bronchial allergy-like symptoms were increased in IDDM patients in comparison to a control population. However there was a small decrease (not significant) in prevalence of positive atopy skin tests in diabetic patients in comparison to controls. This suggests that IDDM patients have an important load of allergy-like symptoms that are not linked to an IgE sensitization.
本研究的目的是调查1型糖尿病患者和非糖尿病对照组的过敏症状、特应性皮肤点刺试验结果之间可能存在的关系。
通过病史评估50名1型糖尿病患者和50名健康对照者的过敏性疾病。所有受试者均使用一组常见的吸入性和食物过敏原进行皮肤点刺试验，以检测特应性致敏情况。
虽然糖尿病组中有56%的患者报告有类似过敏的呼吸道症状，但只有22%的患者皮肤试验呈阳性。对照组中有22%的人有过敏症状，34%的病例皮肤点刺试验呈阳性。
与对照组相比，胰岛素依赖型糖尿病（IDDM）患者的鼻和支气管类似过敏的症状有所增加。然而，与对照组相比，糖尿病患者特应性皮肤试验阳性的患病率略有下降（不显著）。这表明IDDM患者有大量类似过敏的症状，但与IgE致敏无关。
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