结核病的社会成本:德克萨斯州塔兰特县,2002 年。

The societal cost of tuberculosis: Tarrant County, Texas, 2002.

机构信息

School of Public Health, University of North Texas Health Science Center at Fort Worth, Ft. Worth, TX 76107, USA.

出版信息

Ann Epidemiol. 2010 Jan;20(1):1-7. doi: 10.1016/j.annepidem.2009.09.004.

Abstract

PURPOSE

Cost analyses of tuberculosis (TB) in the United States have not included elements that may be prevented if TB were prevented, such as losses associated with TB-related disability, personal and other costs to society. Unmeasured TB costs lead to underestimates of the benefit of prevention and create conditions that could result in a resurgence of TB. We gathered data from Tarrant County, Texas, for 2002, to estimate the societal cost due to TB.

METHODS

We estimated societal costs due to the presence or suspicion of TB using known variable and fixed costs incurred to all parties. These include costs for infrastructure; diagnostics and surveillance; inpatient and outpatient treatment of active, suspected, and latent TB infection (LTBI); epidemiologic activities; personal costs borne by patients and by others for lost time, disability, and death; and the cost of secondary transmission. A discount rate of 3% was used.

RESULTS

During 2002, 108 TB cases were confirmed in Tarrant County, costing an estimated $40,574,953. The average societal cost per TB illness was $ 376,255. Secondary transmission created 47% and pulmonary impairment after TB created 35.4% of the total societal cost per illness.

CONCLUSIONS

Prior estimates have concluded that treatment costs constitute most (86%) TB-related expenditures. From a societal perspective treatment and other direct costs account for little (3.3%) of the full burden. These data predict that preventing infection through earlier TB diagnosis and treatment of LTBI and expanding treatment of LTBI may be the most feasible strategies to reduce the cost of TB.

摘要

目的

美国的结核病(TB)成本分析并未包括如果预防了结核病可能会预防的因素,例如与结核病相关的残疾、个人和社会成本相关的损失。未计量的结核病成本导致对预防效益的低估,并造成结核病死灰复燃的条件。我们从德克萨斯州塔兰特县收集了 2002 年的数据,以估计因 TB 造成的社会成本。

方法

我们使用所有各方承担的已知变量和固定成本,来估计因 TB 存在或怀疑而导致的社会成本。这些包括基础设施成本;诊断和监测;活动性、疑似和潜伏性结核感染(LTBI)的住院和门诊治疗;流行病学活动;患者和他人因失去时间、残疾和死亡而承担的个人成本;以及继发传播的成本。使用 3%的贴现率。

结果

2002 年,塔兰特县确诊了 108 例结核病,估计成本为 40574953 美元。每例结核病的平均社会成本为 376255 美元。继发传播造成了 47%的总成本,而 TB 后肺损伤造成了 35.4%的总成本。

结论

之前的估计得出结论,治疗成本构成了大部分(86%)与结核病相关的支出。从社会角度来看,治疗和其他直接成本仅占全部负担的很小一部分(3.3%)。这些数据预测,通过早期结核病诊断和 LTBI 的治疗以及扩大 LTBI 的治疗来预防感染,可能是降低结核病成本的最可行策略。

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