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万古霉素耐药肠球菌在一家三甲医院的爆发:主要通过监测培养指导的措施缺乏效果,以及屎肠球菌和粪肠球菌之间的反应差异。

Outbreak of vancomycin-resistant enterococci in a tertiary hospital: the lack of effect of measures directed mainly by surveillance cultures and differences in response between Enterococcus faecium and Enterococcus faecalis.

机构信息

Infection Control Department of Hospital Brigadeiro of São Paulo, São Paulo, Brazil.

出版信息

Am J Infect Control. 2010 Jun;38(5):406-9. doi: 10.1016/j.ajic.2009.08.010. Epub 2009 Dec 16.

DOI:10.1016/j.ajic.2009.08.010
PMID:20006408
Abstract

To describe the effect of active surveillance to control vancomycin-resistant enterococci (VRE) after an outbreak, 549 surveillance rectal cultures were performed in 308 patients (35% positive). An educational intervention to prevent transmission was implemented. Infection and colonization by VR- Enterococcus faecalis decreased, but Enterococcus faecium persisted despite control measures. Infections by VR-E faecalis fell to zero in 2008. We observed difficulties in controlling colonization with measures directed mainly by surveillance cultures and differences between responses of E faecium and E faecalis.

摘要

为了描述在爆发后通过主动监测来控制耐万古霉素肠球菌(VRE)的效果,对 308 名患者的 549 份直肠监测培养物进行了检测(35%呈阳性)。实施了一项预防传播的教育干预措施。尽管采取了控制措施,但 VR-粪肠球菌的感染和定植仍然减少,而屎肠球菌则持续存在。2008 年,VR-E 粪肠球菌的感染降至零。我们观察到,通过主要基于监测培养物的措施来控制定植存在困难,以及屎肠球菌和粪肠球菌的反应存在差异。

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