Willis Joseph E
Department of Pathology, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.
Clin Colon Rectal Surg. 2007 Aug;20(3):158-66. doi: 10.1055/s-2007-984860.
Since Cuthbert Dukes fundamental work linking cancer stage to prognosis, the pathologist has had an ever-expanding role in the multidisciplinary management of rectal cancer. Gross dissection techniques and histologic evaluation are reviewed. The evolving tumor size, node status, metastasis classification (TNM) staging system is outlined. The pathologist's critical role in correctly assessing circumferential margins and establishing resection adequacy and staging accuracy via lymph node assessment is emphasized.
自从卡斯伯特·杜克斯将癌症分期与预后联系起来的基础工作以来,病理学家在直肠癌的多学科管理中发挥着越来越重要的作用。本文回顾了大体解剖技术和组织学评估。概述了不断发展的肿瘤大小、淋巴结状态、转移分类(TNM)分期系统。强调了病理学家在正确评估环周切缘以及通过淋巴结评估确定切除充分性和分期准确性方面的关键作用。