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英国结直肠癌的管理:现状及挑战。

Colorectal cancer management in the United Kingdom: current practice and challenges.

机构信息

LSE Health, London School of Economics, Houghton Street, London, WC2A 2AE, UK.

出版信息

Eur J Health Econ. 2010 Jan;10 Suppl 1:S85-90. doi: 10.1007/s10198-009-0202-1.

Abstract

This paper explores the current situation of colorectal cancer (CRC) management in the UK. Colorectal cancer is the third leading cause of cancer death in the UK, and the second and third leading cause of new cancer cases in women and men, respectively. These figures have increased over the past decade and, coupled with poorer survival rates compared to the European average and an ageing population, have recently led to the implementation of national screening in 2007-2009. Staffing adjustments are being made in preparation for national CRC-related demands, and national treatment guidelines are currently being revised. Access to new targeted treatments, however, is very limited due to negative NICE guidance and access is granted to only a select few. Targets have been created with regards to time to diagnosis and treatment, which are generally being met by the majority of hospitals. Overall, the focus on screening activities in the UK will hopefully result in fewer end-stage CRC cases and associated costlier treatments.

摘要

本文探讨了英国结直肠癌(CRC)管理的现状。结直肠癌是英国癌症死亡的第三大原因,也是女性和男性新癌症病例的第二大和第三大原因,分别。这些数字在过去十年中有所增加,再加上与欧洲平均水平相比生存率较差,以及人口老龄化,最近导致 2007-2009 年实施了全国性筛查。正在进行人员调整,以准备应对全国范围内与 CRC 相关的需求,目前正在修订国家治疗指南。然而,由于 NICE 的负面指导意见,新的靶向治疗方法的可及性非常有限,只有少数人获得了治疗机会。已经制定了关于诊断和治疗时间的目标,大多数医院都能达到这些目标。总的来说,英国对筛查活动的重视有望减少晚期 CRC 病例和相关的更昂贵的治疗费用。

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