The use of seromuscular tapered ileal tube in ureteral replacement: an experimental model.

PURPOSE

To assess the capability of urothelium to proliferate, creep and line the inner surface of the interposed seromuscular tapered ileal tube.

MATERIALS AND METHODS

Under general anesthesia, 15 female dogs underwent resection of 5 cm of the mid ureter and replaced with tapered seromuscular ileal tube stented for 6 weeks. The animals were sacrificed, and cross section of the ileal ureters were examined histologically for the lining cells.

RESULTS

Multilayer of transitional epithelium was seen covering all the inner surface of the interposed seromuscular tube at the end of 6 weeks. Excessive inflammatory cell infiltration was a prominent finding in the submucosal layer.

CONCLUSION

Transitional epithelium has the capability to proliferate, grow and cover the inner surface of the interposed seromuscular ileal tube. Urothelium lining avoid the metabolic complications of the intestinal mucosa.