Colliers Annelies, Verster Ann, Van Puyenbroeck Karolien, Stalpaert Michel, Van Royen Paul, Verhoeven Veronique
Department of General Practice, University of Antwerp, Belgium.
Int J Adolesc Med Health. 2009 Jul-Sep;21(3):343-6. doi: 10.1515/ijamh.2009.21.3.343.
In this study we examine the attainability and usefulness of opportunistic screening for Chlamydia trachomatis infection based on self-assessed risk, among university students in Belgium.
A self-administered questionnaire was filled out by students (n = 243, 77.8% female, 22.2% male), who were asked to assess their own risk, to decide if their participation was useful, and to collect a first-void urine sample. Specimens were refrigerated and delivered to the laboratory on the same day. Screening for C. trachomatis DNA was performed by PCR. A Positive result was confirmed by another amplification assay.
Two hundred forty three students took part in the study. One hundred thirteen participants did not meet the inclusion criteria. Ages varied from 18 to 39 years, with a mean age of 21.49 years. The overall prevalence of C. trachomatis infection was 2.9%. The prevalence of C. trachomatis infection in the group of students who met the inclusion criteria was 5.4%. Having a new partner in the past six months and having had more than one partner in the last year were the most frequent reported risk factors in male and female participants.
Screening students is a useful and feasible strategy to diagnose asymptomatic chlamydial infection. However assessing their own risk of infection seemed difficult for students. The overscreening of youngsters not at risk and the limited participation of males should get extra attention.
在本研究中,我们调查了比利时大学生基于自我评估风险进行沙眼衣原体感染机会性筛查的可及性和实用性。
学生(n = 243,77.8%为女性,22.2%为男性)填写一份自填式问卷,被要求评估自身风险,决定参与筛查是否有用,并收集首次晨尿样本。样本冷藏并于当天送至实验室。通过聚合酶链反应(PCR)检测沙眼衣原体DNA。阳性结果通过另一种扩增检测进行确认。
243名学生参与了研究。113名参与者不符合纳入标准。年龄从18岁至39岁不等,平均年龄为21.49岁。沙眼衣原体感染的总体患病率为2.9%。符合纳入标准的学生组中沙眼衣原体感染患病率为5.4%。在过去六个月有新伴侣以及在过去一年有不止一个伴侣是男性和女性参与者报告的最常见风险因素。
对学生进行筛查是诊断无症状衣原体感染的一种有用且可行的策略。然而,学生似乎难以评估自身感染风险。对无风险青少年的过度筛查以及男性参与度有限应予以特别关注。