立体定向神经外科治疗药物成瘾。
Stereotactic neurosurgical treatment of drug addiction.
机构信息
National Institute on Drug Dependence, Peking University, 38, Xue Yuan Road, Beijing 100083, China.
出版信息
Am J Drug Alcohol Abuse. 2009;35(6):391-3. doi: 10.3109/00952990903312478.
BACKGROUND
Stereotactic neurosurgery is a well-developed and accepted treatment for movement disorders like Parkinson's disease.
OBJECTIVE
Review use of this neurosurgical intervention to treat drug addiction since the 1960s.
METHODS
Literature review of case and series reports.
RESULTS
Stereotactic neurosurgery has shown promising results in reducing drug addiction, but it has also caused severe side effects. Thus, surgeons have sought to refine the stereotactic lesion procedure and its target over the past 50 years.
CONCLUSIONS AND SIGNIFICANCE
Recent developments in stereotactic technique and deep brain stimulation (DBS) may make stereotactic neurosurgery a viable and reversible treatment for drug addiction.
背景
立体定向神经外科是一种治疗运动障碍（如帕金森病）的成熟且被广泛接受的治疗方法。
目的
回顾自 20 世纪 60 年代以来，使用这种神经外科干预手段治疗药物成瘾的情况。
方法
对病例和系列报告的文献进行回顾。
结果
立体定向神经外科在减少药物成瘾方面显示出了有前景的结果，但也引起了严重的副作用。因此，在过去的 50 年里，外科医生一直在寻求改进立体定向损伤程序及其靶点。
结论和意义
立体定向技术和深部脑刺激（DBS）的最新进展可能使立体定向神经外科成为一种可行且可逆转的药物成瘾治疗方法。
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