中国田间和疫苗株蓝舌病毒 S10 RNA 节段的遗传多样性。
Genetic diversity of the S10 RNA segment of field and vaccine strains of bluetongue virus from the P. R. China.
机构信息
College of Animal Science and Technology, Yunnan Agricultural University, 650201 Kunming, China.
出版信息
Arch Virol. 2010 Feb;155(2):281-6. doi: 10.1007/s00705-009-0574-7. Epub 2009 Dec 18.
Bluetongue virus (BTV) infection of ruminants is endemic throughout tropical and subtropical regions of the world. However, the molecular epidemiology of BTV infection in China has not yet been reported. In this study, the S10 gene segments from 30 BTV isolates, one attenuated BTV strain, one vaccine BTV strain, and one South Africa BTV prototype strain, were sequenced. Phylogenetic analysis of the S10 genes showed that Chinese BTV isolates could be classified into two phyletic subgroups, and the clustering of Chinese BTV viruses was dependent on their geographical origin and the number of generations for which they had been propagated, rather than their host species or year of isolation.
蓝舌病病毒（BTV）感染是反刍动物的地方流行性疾病，流行于世界热带和亚热带地区。然而，中国 BTV 感染的分子流行病学尚未有报道。在本研究中，对 30 株 BTV 分离株、1 株弱毒 BTV 株、1 株疫苗 BTV 株和 1 株南非 BTV 原型株的 S10 基因片段进行了测序。S10 基因的系统进化分析表明，中国 BTV 分离株可分为两个系统发育亚群，中国 BTV 病毒的聚类既不依赖于宿主种类，也不依赖于其分离年份，而是与它们的地理起源和传代次数有关。
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