Department of Psychiatry and Psychology and Behavioral Health Research Program, Mayo Clinic College of Medicine, 200 First Street Southwest, Charlton 6-273, Rochester, MN 55901, USA.
Nicotine Tob Res. 2010 Feb;12(2):79-87. doi: 10.1093/ntr/ntp180. Epub 2009 Dec 17.
Among Alaska Native women residing in the Yukon-Kuskokwim (Y-K) Delta region of Western Alaska, about 79% smoke cigarettes or use smokeless tobacco during pregnancy. Treatment methods developed and evaluated among Alaska Native pregnant tobacco users do not exist. This pilot study used a randomized two-group design to assess the feasibility and acceptability of a targeted cessation intervention for Alaska Native pregnant women.
Recruitment occurred over an 8-month period. Enrolled participants were randomly assigned to the control group (n = 18; brief face-to-face counseling at the first visit and written materials) or to the intervention group (n = 17) consisting of face-to-face counseling at the first visit, four telephone calls, a video highlighting personal stories, and a cessation guide. Interview-based assessments were conducted at baseline and follow-up during pregnancy (>or=60 days postrandomization). Feasibility was determined by the recruitment and retention rates.
The participation rate was very low with only 12% of eligible women (35/293) enrolled. Among enrolled participants, the study retention rates were high in both the intervention (71%) and control (94%) groups. The biochemically confirmed abstinence rates at follow-up were 0% and 6% for the intervention and control groups, respectively.
The low enrollment rate suggests that the program was not feasible or acceptable. Alternative approaches are needed to improve the reach and efficacy of cessation interventions for Alaska Native women.
在阿拉斯加西部育空-科尤库克三角洲地区居住的阿拉斯加原住民女性中,约有 79%在怀孕期间吸烟或使用无烟烟草。针对阿拉斯加原住民怀孕烟草使用者开发和评估的治疗方法并不存在。这项试点研究采用随机两群组设计,评估针对阿拉斯加原住民孕妇的有针对性的戒烟干预措施的可行性和可接受性。
招募工作在 8 个月内进行。纳入的参与者被随机分配到对照组(n=18;第一次就诊时进行简短的面对面咨询和书面材料)或干预组(n=17),包括第一次就诊时的面对面咨询、四次电话咨询、一个突出个人故事的视频和一个戒烟指南。在基线和妊娠期间(>或=60 天随机分组后)进行基于访谈的评估。可行性通过招募和保留率来确定。
参与率非常低,只有 12%的合格女性(35/293)参加。在纳入的参与者中,干预组(71%)和对照组(94%)的研究保留率均很高。干预组和对照组在随访时的生物化学确认戒烟率分别为 0%和 6%。
低参与率表明该方案不可行或不可接受。需要采取替代方法来提高针对阿拉斯加原住民女性的戒烟干预措施的覆盖面和效果。