Wenstrom K D, Williamson R A, Weiner C P, Sipes S L, Yuh W T
Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City.
Obstet Gynecol. 1991 Apr;77(4):529-32.
Thirteen women whose fetuses had intracranial defects on ultrasound examination were offered magnetic resonance imaging (MRI) without charge. All fetuses were paralyzed with pancuronium before the study, which lasted approximately 1 hour. With the mother in the left lateral decubitus position to minimize transmitted maternal aortic pulsation, T1-weighted images were obtained using a Picker 0.5-tesla superconductive unit. Magnetic resonance imaging provided excellent detail of intracranial anatomy in all cases. In four of the 13 fetuses, the MRI diagnosis differed from that of ultrasound and ultimately proved correct. In another three, MRI added greatly to the ultrasound diagnosis by delineating intracranial anatomy more precisely. In the remaining six cases, MRI confirmed the ultrasound impression. For circumstances in which the ultrasound diagnosis is unclear or antenatal intervention might require exact knowledge of anatomical detail, the additional information provided by MRI may justify its cost.
13名经超声检查发现胎儿存在颅内缺陷的孕妇免费接受了磁共振成像（MRI）检查。在研究开始前，所有胎儿均用潘库溴铵使其麻痹，研究持续约1小时。母亲取左侧卧位以尽量减少母体主动脉搏动的传导，使用Picker 0.5特斯拉超导设备获取T1加权图像。在所有病例中，磁共振成像均能提供颅内解剖结构的清晰细节。13例胎儿中有4例，MRI诊断与超声诊断不同，最终证明MRI诊断正确。另外3例中，MRI通过更精确地描绘颅内解剖结构，极大地补充了超声诊断。在其余6例中，MRI证实了超声的诊断结果。对于超声诊断不明确或产前干预可能需要精确了解解剖细节的情况，MRI提供的额外信息可能使其成本合理。
