Shioiri Masanobu, Seike Kazuhiro, Kametaka Hisashi, Makino Hironobu, Miura Seiki, Okubo Yoshiyuki, Fujisaki Kaoru, Koyama Takashi
Department of Surgery, Odawara Municipal Hospital.
Gan To Kagaku Ryoho. 2009 Nov;36(12):2357-8.
A 68-year-old man visited our hospital due to constipation. A hard mass was palpated in the left side abdomen. Several examinations could point out a large left sided retroperitoneal tumor. Because the tumor was adherent to the descending colon, both were removed. Based on histological and immunohistochemical inspection, the tumor was diagnosed as malignant fibrous histocytoma (MFH) on retroperitoneum. No treatment was undergone as the postoperative course was good, however, computed tomography (CT) for 8 months after the surgery showed the sign of local recurrence. It has been reported that the prognosis of MFH was very poor and a surgical resection was the only treatment for MFH, or we are expecting to find an effective treatment quickly such as a new combined chemotherapy.
一名68岁男性因便秘前来我院就诊。在左侧腹部可触及一硬块。多项检查提示左侧腹膜后有一巨大肿瘤。由于肿瘤与降结肠粘连,遂将二者一并切除。根据组织学和免疫组化检查,该肿瘤被诊断为腹膜后恶性纤维组织细胞瘤(MFH)。术后恢复良好,未进行其他治疗,然而,术后8个月的计算机断层扫描(CT)显示有局部复发迹象。据报道,MFH的预后非常差,手术切除是MFH的唯一治疗方法,或者我们期望能尽快找到一种有效的治疗方法,如新型联合化疗。